Restricted cubic spline analyses found that after adjusting for all confounding factors included in this study, the inflection point occurs when the ApoB/ApoA1 ratio is 0.7, which means that when the ratio of ApoB/ApoA1 was less than 0.70, the prevalence of HCC in LC patients decreased with ratio of ApoB/ApoA1. Here, APOA1 is linked to laryngotracheoesophageal cleft.