DNMT3A and acute lymphoblastic leukemia: HOXA subgroup assignment was more frequent in adult T-ALL (24.5% vs. 13.7%) comprising samples with fusions for KMT2A, MMLT10, and HOXA10. This age distribution with higher frequencies for HOXA subgroup is in line with a higher rate of mutations in epigenetic regulators (most prominent PHF6 and DNMT3A) and members of JAK/STAT pathway compared to published data [5, 6].