Instead, we observed that 4EBP1/2 protect even p53 deficient cells, including 4EBP1/2 WT MEFs −which are KO for p53− and Kelly neuroblastoma cells that carry an inactivating TP53 mutation, suggesting rather that 4EBP1/2 protect cells during glucose starvation independently of p53. The gene discussed is TP53; the disease is neuroblastoma.