The first ecDNA was present in the tumor and P14 and a second ecDNA at P0 and P8 that had additional segments e1 containing C12orf77 (chr12:251389380-25148653) and e12 containing LMNTD1 mapping to chr12:25628038-25636598 (Figs. 4E, 5E). This evidence concerns the gene LMNTD1 and neoplasm.