Given the findings in the GO2 cohort, the association between CXCL10 (as a key determinant of DDIR status) and the TME was subsequently explored in transcriptomic data from an external cohort of 306 oesophageal and gastroesophageal junctional adenocarcinoma samples obtained from the OCCAMS consortium (Supplementary Table S14, available at https://doi.org/10.1016/j.esmoop.2024.103450). The gene discussed is CXCL10; the disease is gastroesophageal junction adenocarcinoma.