Interestingly, through qPCR validation, we were able to confirm that CRLF2, SORCS2, SORL1, IL7R, CSF2RA, LRIG1, SIRPA, MDGA1, IL1R1, PSG5, and PDGFRB all exhibited an increasing trend in expression during cancer deformation (Fig 3B). Here, CRLF2 is linked to cancer.