Hemochromatosis in whites of western European descent is associated with homozygosity for HFE p.C282Y (rs1800562), a common missense allele of the homeostatic iron regulator (chromosome 6p22.2) in linkage disequilibrium with human leukocyte antigen (HLA)-A*03 [1, 2]. This evidence concerns the gene HLA-A and hemochromatosis type 1.