Another study used exosomes as nanocarriers to transport circDIDO1 to GC cells; results showed that circDIDO1 can counterbalance the effects of miR-1307-3p overexpression in GC by serving as a miRNA sponge to stimulate SOCS2 expression, which in turn prevents the proliferation of GC cells [113]. This evidence concerns the gene SOCS2 and gastric cancer.