ALB and cancer: The Kim group developed a redox triggered NO prodrug (SISIN-1) that can target TDLE (Fig. 28(A)).92 Since albumin has the ability to enhance lymphatic drainage and endocytosis in cancer cells,93,94 AL-SISIN-1 formed by binding SISIN-1 to albumin is able to efficiently deliver NO to TDLE, thereby inhibiting tumor metastasis.