While, the primary immune cell subtypes promoting the incidence of glioblastoma include CD62L– HLA DR++ monocyte % monocyte (OR = 1.522, CI = 1.004–2.307, P = 0.048), CD4+CD8+ T cell % leukocyte (OR = 1.387, CI = 1.031–1.866, P = 0.031), Lymphocyte Absolute Count (OR = 1.369, CI = 1.050–1.786, P = 0.020), Granulocyte Absolute Count (OR = 1.363, CI = 1.044–1.780, P = 0.023). This evidence concerns the gene CD4 and glioblastoma.