Specifically, NOD2 was associated with CD (Regional enteritis, 555.1, P = 1.38 × 10−4 in UK Biobank and P = 2.56 × 10−2 in BioMe BioBank) and IBD (P = 4.49 × 10−2 in UK Biobank and P = 2.29 × 10−2 in BioMe BioBank) (Fig. 4B and Additional file 2: Table S18). This evidence concerns the gene NOD2 and enteritis.