JAK1 and essential tremor: Additionally, JAK1 was associated with essential tremor (333.1, P = 1.03 × 10−2) and RB1CC1 displayed an association with cholangitis (575.1, P = 1.02 × 10−2) and IL6ST with noninfectious gastroenteritis in UK Biobank (558, P = 3.14 × 10−2).