QSOX1 and colorectal carcinoma: Ganiga et al. reported that CAF-derived EVs display abundant EGF-like repeats and discoidin domains 3 (EDIL3), while NF-derived EVs exert suppressed quiescin sulfhydryl oxidase 1 (QSOX1) expression, and both markers are suppressed in CRC as opposed to corresponding controls [205] (Table 3).