AFP and hepatocellular carcinoma: In this study, we implemented six machine learning algorithms including XGBoost, logistic regression (LR), support vector machine (SVM), random forest (RF), K-nearest neighbor (KNN), and decision tree (ID3) to predict 1-, 3- and 5-year survival of patients with AFP-positive HCC, using data retrieved from the Surveillance, Epidemiology, and End Results (SEER) database.