IPP- or HMBPP-induced γδ T cells can readily produce the anti-tuberculosis cytokines IFN-γ and TNF-α, which are capable of inducing macrophage or monocyte activation and play important roles in the body's antitumour, anti-infection, immunomodulation, immunosurveillance, and maintenance of immune tolerance abilities [8–11]. The gene discussed is TNF; the disease is tuberculosis.