The majority of patients had a positive expression of PD-L1 (71.8%), were receiving ICI combination treatments (94.7%), showed absence of brain/liver metastasis (86.3%), had no comorbidities of hypertension and diabetes (66.5%), had a body mass index (BMI) below 24 kg m−2 (67.0%) and had a neutrophil-to-lymphocyte ratio (NLR) below 5 (78.0%). Here, CD274 is linked to hypertensive disorder.