In further support of the MUC1-C/XIST pathway, we found that MUC1-C and XIST regulate common genesets associated with activation of (i) miRNAs, such as miR-21, (ii) lncRNAs NEAT1 and MALAT1, and protein encoding genes that are linked to inflammation and dysregulated in cancer. Here, MALAT1 is linked to cancer.