The following statistically significant differentially expressed genes during bed rest (HDT2 vs HDT30/60) have also been associated with different types of anemia including: Diamond-Blackfan anemia (TMSB10), alpha thalassemia (ATRX), Fanconi anemia (MOSPD2, FAAP24, FANCB, CNPY2, H2AC13), microcytic anemia (TMPRSS6). The gene discussed is TMPRSS6; the disease is Alpha-thalassemia.