Individuals in the early stages of idiopathic membranous nephropathy exhibited elevated levels of circulating CD14 + /CD163 + , CD14 + /CD163 + /CD206 + , and CD14 + /CD163 + /CD206 + /CD115+ macrophages compared to healthy controls [148]. The gene discussed is CD163; the disease is idiopathic membranous glomerulonephritis.