TGFB1 and renal fibrosis: The pro-fibrotic consequence of TGF-β1 was extinct through a marked decrease in bone marrow-derived macrophages expressing GFP + , F4/80 + , and a-SMA + , as they underwent macrophage myofibroblast transformation (MMT), as demonstrated by [102] Wang et al. Consequently, renal fibrosis was diminished in the mouse study subjected to unilateral ureteral obstruction (UUO) [103].