Additionally, distinct populations of M2 macrophages, characterized by CD163 + and CD206 + markers, were predominantly found in fibrous crescents and were more prevalent in lupus nephritis (LN) and ANCA-associated vasculitis compared to IgA nephropathy and Henoch Schönlein purpura glomerulonephritis [88, 140]. The gene discussed is CD163; the disease is lupus nephritis.