ACE2 and diabetes mellitus: Since the elderly have lower resistance to the virus, the COVID-19 pandemic has posed unparalleled health risks to this demographic group, especially those with underlying diseases, such as hypertension, diabetes, cardiovascular disease, and chronic respiratory disease.2,3 Research indicates that elderly individuals have higher levels of angiotensin-converting enzyme 2 (ACE2) compared to younger adults,4 which elevates their vulnerability to SARS-CoV-2 infection.