STEAP2 and ovarian carcinoma: Furthermore, we analyzed the TCGA transcriptome data of clinical ovarian cancer samples, which showed that ovarian cancer cells upregulated genes involved in iron uptake and utilization, such as transferrin receptor (TFRC), STEAP2/DMT1, and iron storage genes (FTH1/FTL), while downregulating the expression of iron exporter gene (SLC40A1, also known as FPN).