GPVI-expressing mice presented a positive z-scoring for genes related with melanoma progression and detrimental prognosis (Mlana, Mc1r, Rab38, Cd63, Mlph, Pmel, Myo7a, Satb2), immune checkpoint proteins (ICP) (Cd276, Sirpa, Lgals3) and cell cycle progression (Cdk1, Ccnb1, Cdca2, Ccda8, Cdc20, Cdc25a, Mcm2, Mcm3, Mcm5, Top2a, Birc5). Here, PMEL is linked to melanoma.