TNF and cancer: The number of death cells in SA-b-gal-positive DLD1, HCT116, or RKO was more than that in SA-b-gal-positive SW480 or SW620, and DLD1, HCT116 and RKO are dMMR cancer cell lines, SW480 and SW620 are pMMR cancer cell lines (Fig. 1), it showed that SA-b-gal-positive dMMR cancer cell lines were more sensitive than SA-b-gal-positive pMMR cancer cell lines to co-treatment of IFN-γ and TNF-α (Fig. 3b, c).