High levels of circulating inflammatory proteins such as IL-1β, IL-6, IL-8, IL-13, TNF, neutrophil gelatinase-associated lipocalin, myeloperoxidase (MPO), macrophage inflammatory protein (MIP)-1β, and monocyte chemoattractant protein-1 (MCP-1) may be potential predictive markers for impaired cognition [46-48]. The gene discussed is MPO; the disease is Cognitive impairment.