PECAM1 and posterior cortical atrophy: PECAM1 (Platelet Endothelial Cell Adhesion Molecule1) or CD31 is mainly involved in the regulation ofcell–cell interactions and angiogenesis.42 A previous study identified that the expression of PECAM1 is associated with the early angiogenic switch andthe recruitment of new vasculature to lesions indicative of advancedprostatic epithelial neoplasia,43 whichhighlights the important role that PECAM1 plays inthe development of new blood vessels during the progression of PCa.