However, several recent reviews have concluded there may be links between mTBI and neurodegenerative pathology, with mTBI resulting in AD pathology, including increased amyloid-beta plaques, neurofibrillary tangles, Tau and Lewy pathology (Washington et al. 2016; Wilson et al. 2017; Ramos-Cejudo et al. 2018). This evidence concerns the gene MAPT and Alzheimer disease.