Cancer gene panel testing of the retroperitoneal tumor sample showed a base substitution in ARID1A (splice site 2251+2T>G), duplication of exons 5–31 in NOTCH2, frameshift mutation in MSH6 (D387fs*4), and deletion of exons 5–9 in NF2, none of which were treatable target in the present case. The gene discussed is NF2; the disease is neoplasm.