VEGFA and Insulin resistance: Thus, VEGF promotes skeletal muscle capillary proliferation and function (Ishii et al. 2002, Olsson et al. 2006, Wagner et al. 2011, Hellsten & Hoier 2014, Olfert et al. 2010, Bonner et al. 2013) in many tissues of the adult, and deletion of VEGF in transgenic mice results in capillary regression and insulin resistance (Bonner et al. 2013).