As for the dual role of TLR3, it has been found that pro‐ and antitumor effects have been observed in the same cell line depending on the mode of delivery of the TLR3‐ligand, with surface stimulation leading to protumoural effects whereas cytoplasmic stimulation has been antitumoral in two breast cancer cell lines.50 The gene discussed is TLR3; the disease is breast cancer.