As previously reported for CRC, a study by Liang et al. (2020) established a prognostic model composed of 10 ferroptosis-related genes also for HCC: GPX4, NAD(P)H Quinone Dehydrogenase 1 (NQO1), Solute Carrier Family 1 Member 5 (SLC1A5), Acetyl-CoA Carboxylase Alpha (ACACA), Acyl-CoA Synthetase Lon Chain Family Member 3 (ACSL3), CISD1, Cysteinyl-TRNA Synthetase 1 (CARS1), Glucose-6-Phosphate Dehydrogenase (G6PD), GPX4, and Solute Carrier Family 1 Member 5 (SLC1A5). This evidence concerns the gene GPX4 and hepatocellular carcinoma.