In a phase 1 study exploring Kasai-G-CSF sequential therapy for BA, G-CSF safely mobilized hematopoietic stem cells in Kasai children, potentially enhancing short-term biliary drainage and mitigating cholangitis.28 Nonetheless, the efficacy outcomes of sequential adjuvant Kasai and G-CSF therapy in phase 2 have yet to be determined. This evidence concerns the gene CSF3 and cholangitis.