Then, we analyzed the expression of other subunits of the MCU complex, including MCUB, EMRE, MICU1, MICU2, and MICU3 in gastric cancer and adjacent tissues, and showed that MCUB, which co-composed of Ca2+ channels with MCU, was highly expressed in gastric cancer tissues, and the positive regulatory subunit MICU1 and MICU2 were highly expressed in gastric cancer tissues, and the negative regulatory subunit MICU3 was under expressed in gastric cancer tissues (P<0.05), as shown in Figures 1E–I. This evidence concerns the gene SMDT1 and gastric cancer.