The statistical analysis showed that ALP (P <0.001), PPAT volume (P <0.001), normalized PPAT (P <0.001), PSA (P =0.024), cT (P <0.001), cN (P <0.001) and Grading Groups (P =0.010, were significantly different between the patients in the two groups, whereas age (P =0.186), BMI (P =0.734), serum calcium (P =0.847), serum phosphorus (P =0.873), prostate volume (P =0.981), diabetes (P =0.193), hypertension (P =0.942) and coronary heart disease (P =0.972) were not statistically significant. The gene discussed is KLK3; the disease is diabetes mellitus.