Significantly higher BMI in del15q subjectsSignificantly higher HbA1c in del15q subjects without diabetes, compared with mUPD patients.No differences in endocrine profile between del15q and mUPD.Higher proportion of percent body fat, adipocyte size and insulin resistance (related to BMI) in UPD compared with del15q.Lower BMI, percentage of body fat and adipocyte size in del15q subjects treated with GH, compared with mUPD. The gene discussed is GH1; the disease is diabetes mellitus.