Significant differences between the suicide attempters, patients with MDD and controls were detected in the following variables: age, education, antidepressant use, DHEA levels, income, diastolic blood pressure, heart rate, HAM-D total score, SSI total score, history of past episode of depression, SA history, family history of depression, current smoking, plasma CRP levels, plasma TNF-alpha levels, and self-reported alcohol use. This evidence concerns the gene TNF and depressive disorder.