COL1A1 (P = 8.9e−05), COL1A2 (P = 0.0015), COL4A1 (P = 5.5e−07), FN1 (P = 1.1e−05), COL6A3 (P = 0.0015), and THBS2 (P = 1.2e−06) were significantly associated with poor survival probability in patients with GC, and THBS1 (p = 0.073) was not significantly associated with prognosis and survival rate in patients with GC. This evidence concerns the gene COL1A1 and gastric cancer.