Among the HCC patients, no mutations were observed in twelve other regulators, namely DNMT3B, MBD3, MBD4, ZBTB4, UHRF1, UHRF2, UNG, NTHL1, SMUG1, MBD2, ZBTB33 and QSER1 (Figure 2A). Here, ZBTB33 is linked to hepatocellular carcinoma.