DNMT3B and hepatocellular carcinoma: Among the HCC patients, no mutations were observed in twelve other regulators, namely DNMT3B, MBD3, MBD4, ZBTB4, UHRF1, UHRF2, UNG, NTHL1, SMUG1, MBD2, ZBTB33 and QSER1 (Figure 2A).