To find the cutoff values for GFAP and NfL associated with an elevated risk of dementia, we grouped their expression by quartiles and found that interval 4 of both GFAP and NfL significantly increased the risk of developing dementia (Additional file 1: Table S8), and the cutoff values at this point were 0.363 for GFAP and 0.353 for NfL. This evidence concerns the gene GFAP and dementia.