LEP and endothelial dysfunction: Our study seems to support this hypothesis with some correlations between US-measured Omental fat and leptin or endothelial dysfunction markers (Ultrasensitive-CRP and microalbuminuria), especially in the intensified combined Metformin + Dapaglifozin treated group (although addition of dapaglifozin does not seem to induce greater omental fat loss to metformin alone).