IL1B and synovitis: A Venn diagram revealed 23 common targets, as shown in Fig. 7B. Particularly, IL-6 was among these common targets, as illustrated in Fig. 7C. Using a protein network interaction map, we observed that IL-6 was closely linked to several inflammatory factors, including IL1B, IL2, IL3, IL10, as depicted in Fig. 7D. Consequently, we speculated that DPA, as an active component in fish oil, might serve as a potential agent for synovitis treatment.