Population differences in smoking, alcohol use, some laboratory tests (Glycohemoglobin, Triglyceride, low-density lipoprotein, high-density lipoprotein, uric acid, C-reactive protein, fibrinogen), and clinical comorbidities (e.g., Hypertension, Diabetes Mellitus, Congestive Heart Failure, Cancer, Osteoporosis, Arthritis) varied according to the definition of low muscle mass. This evidence concerns the gene CRP and osteoporosis.