These signals belonged to five different loci (table 1), two of which are established risk loci for giant cell arteritis, 6p21.32 (HLA-DQA1, rs41269974; p=1·60 × 10–87; OR 2·03 [95% CI 1·90–2·17]) and 6q26 (PLG, rs4252114; p=1·38 × 10–13; OR 1·25 [1·18–1·32]). Here, HLA-DQA1 is linked to temporal arteritis.