ADA2 and carcinoma: The regions of interest (ROIs) were categorized into four histological areas using morphological markers (Figures 5A and 5B); 69 ROIs were classified as carcinoma deserted (Pan-cytokeratin [PanCK] rich/CD45 poor), 61 as carcinoma infiltrated (PanCK rich/CD45 rich), 69 as stroma deserted (PanCK poor/CD45 poor), and 61 as stroma infiltrated (PanCK poor/CD45 rich).