SMC3 and Cornelia de Lange syndrome: demonstrate that individuals with heterozygous, predicted loss‐of‐function variants in SMC3 are survivable, and phenotypes associated with variable developmental delay, growth deficiency, and/or facial dysmorphism, that are milder than but overlapping with that of SMC3 missense/in‐frame indel variants present in CdLS cohorts (Ansari et al., 2024).