GPT and obesity due to melanocortin 4 receptor deficiency: (Bifidobacterium pseudocatenulatum SPM 1204, Bifidobacterium longum SPM 1205, and Bifidobacterium longum SPM 1207) were added to high-fat diet-induced rats with obesity, they decreased the body and fat weights, blood serum parameters such as total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) low-density lipoprotein cholesterol (LDL-C), alanine aminotransferase (ALT), TG, glucose, and lipase levels), and harmful enzyme activities (β-glucosidase, β-glucuronidase, and tryptophase) and efficiently augmented fecal LAB numbers [48].