A single-nucleotide polymorphism, rs1799998, in the aldosterone synthase gene, Cytochrome P450 Family 11 Subfamily B Member 2 (CYP11B2), has also been reported to associate with cardiovascular diseases, such as atrial fibrillation [61] or intracranial large artery stenosis [62]. The gene discussed is CYP11B2; the disease is cardiovascular disorder.