Of particular interest were differently expressed proteins in tumors from mice fed adequate as compared to excess iron, which included those involved in cell integrity (ANPEP: alanyl (membrane) aminopeptidase; DPP7: dipeptidyl-peptidase; PSMA1: proteosome subunit; and SERPINB1: serine peptidase inhibitor) and adaptive response to reactive oxygen species (SOD1: superoxide dismutase); SOD2; and PRDX1: peroxiredoxin), possibly related to the increased cell turnover and growth of tumor cells and concurrent adaptation of tumors to increased intraluminal dietary iron. Here, ANPEP is linked to neoplasm.