ADRB3 and obesity due to melanocortin 4 receptor deficiency: The GRSBMI included the SNPs TMEM rs18939583, ADRB3 rs4994, FTO rs9939609, MC4R rs2331841, ADCY3 rs10182181, BDNF rs925946, GIPR rs11672660, and BDNF rs6265, each of which has been previously linked to obesity [15] and was included in different GRS studies related to obesity predisposition in other populations, but in different SNPs composing the GRS.