The usefulness of CA125, HE4, ROMA, RMI, and subjective assessment (SA) in the preoperative diagnosis of ovarian tumors was compared by Janas Ł et al. [36], who obtained AUCs for CA125, HE4, ROMA, RMI, and SA of 0.819, 0.909, 0.911, 0.895, and 0.895, respectively. Here, WFDC2 is linked to ovarian neoplasm.