SPP1 and ovarian cancer: Lu D et al. [68] investigated 14 biomarkers associated with ovarian cancer, including CA125, MIF- (1macrophage inhibitory factor-1), leptin, prolactin, osteopontin, IGF-II (insulin-like growth factor-II), and autoantibodies to eight proteins: p53, NY-ESO-1, p16, ALPP, CTSD, B23, GRP78, and SSX.