Urinary neutrophil gelatinase-associated lipocalin (NGAL) [10,11,12,13], interleukin (IL)-18 [14,15], and L-type fatty acid-binding protein (L-FABP) [16,17,18] have been identified as potential markers for the early detection of kidney damage before an increase in serum creatinine levels. The gene discussed is LCN2; the disease is Nephropathy.