AFP and neoplasm: Based on this evidence, three Japanese centres have set up new extended criteria: the “Tokyo criteria” (≤5 tumours, each with a diameter ≤5 cm, in combination with serum levels of AFP and of DCP, respectively, of ≤250 ng/mL and ≤450 mAU/mL), the “Kyoto criteria” (≤10 tumours, each with a diameter ≤ 5 cm, in combination with serum DCP ≤ 400 mAU/mL), and, lastly, the “Kyushu criteria” (≤5 cm tumours, in combination with serum DCP ≤ 300 mAU/mL) [9,10,11,12,13,16,18,24,25,26].